Prostate-specific Membrane Antigen Heterogeneity and DNA Repair Defects in Prostate Cancer

BACKGROUND: Prostate-specific membrane antigen (PSMA; folate hydrolase) prostate cancer (PC) expression has theranostic utility. OBJECTIVE: To elucidate PC PSMA expression and associate this with defective DNA damage repair (DDR). DESIGN, SETTING, AND PARTICIPANTS: Membranous PSMA (mPSMA) expression...

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Udgivet i:Eur Urol
Main Authors: Paschalis, Alec, Sheehan, Beshara, Riisnaes, Ruth, Rodrigues, Daniel Nava, Gurel, Bora, Bertan, Claudia, Ferreira, Ana, Lambros, Maryou B.K., Seed, George, Yuan, Wei, Dolling, David, Welti, Jon C., Neeb, Antje, Sumanasuriya, Semini, Rescigno, Pasquale, Bianchini, Diletta, Tunariu, Nina, Carreira, Suzanne, Sharp, Adam, Oyen, Wim, de Bono, Johann S.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6853166/
https://ncbi.nlm.nih.gov/pubmed/31345636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2019.06.030
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