Intra-tracheal administration of a naked plasmid expressing stromal derived factor-1 improves lung structure in rodents with experimental bronchopulmonary dysplasia

BACKGROUND: Bronchopulmonary dysplasia (BPD) is characterized by alveolar simplification and disordered angiogenesis. Stromal derived factor-1 (SDF-1) is a chemokine which modulates cell migration, proliferation, and angiogenesis. Here we tested the hypothesis that intra-tracheal (IT) administration...

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Bibliografiske detaljer
Udgivet i:Respir Res
Main Authors: Guerra, Kasonya, Bryan, Carleene, Dapaah-Siakwan, Frederick, Sammour, Ibrahim, Drummond, Shelly, Zambrano, Ronald, Chen, Pingping, Huang, Jian, Sharma, Mayank, Shrager, Sebastian, Benny, Merline, Wu, Shu, Young, Karen C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852969/
https://ncbi.nlm.nih.gov/pubmed/31718614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1224-6
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