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Frontline Science: Endotoxin‐induced immunotolerance is associated with loss of monocyte metabolic plasticity and reduction of oxidative burst

Secondary infections are a major complication of sepsis and associated with a compromised immune state, called sepsis‐induced immunoparalysis. Molecular mechanisms causing immunoparalysis remain unclear; however, changes in cellular metabolism of leukocytes have been linked to immunoparalysis. We in...

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Bibliografische gegevens
Gepubliceerd in:J Leukoc Biol
Hoofdauteurs: Grondman, Inge, Arts, Rob J. W., Koch, Rebecca M., Leijte, Guus P., Gerretsen, Jelle, Bruse, Niklas, Kempkes, Rosalie W. M., ter Horst, Rob, Kox, Matthijs, Pickkers, Peter, Netea, Mihai G., Gresnigt, Mark S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852552/
https://ncbi.nlm.nih.gov/pubmed/31169935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.5HI0119-018R
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