Frontline Science: Endotoxin‐induced immunotolerance is associated with loss of monocyte metabolic plasticity and reduction of oxidative burst

Secondary infections are a major complication of sepsis and associated with a compromised immune state, called sepsis‐induced immunoparalysis. Molecular mechanisms causing immunoparalysis remain unclear; however, changes in cellular metabolism of leukocytes have been linked to immunoparalysis. We in...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Grondman, Inge, Arts, Rob J. W., Koch, Rebecca M., Leijte, Guus P., Gerretsen, Jelle, Bruse, Niklas, Kempkes, Rosalie W. M., ter Horst, Rob, Kox, Matthijs, Pickkers, Peter, Netea, Mihai G., Gresnigt, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Spotlight on Leading Edge Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6852552/
https://ncbi.nlm.nih.gov/pubmed/31169935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.5HI0119-018R
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