Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria

Somatic mutation signatures may represent footprints of genetic and environmental exposures that cause different cancer. Few studies have comprehensively examined their association with germline variants, and none in an indigenous African population. SomaticSignatures was employed to extract mutatio...

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Détails bibliographiques
Publié dans:Int J Cancer
Auteurs principaux: Wang, Shengfeng, Pitt, Jason J., Zheng, Yonglan, Yoshimatsu, Toshio F., Gao, Guimin, Sanni, Ayodele, Oluwasola, Olayiwola, Ajani, Mustapha, Fitzgerald, Dominic, Odetunde, Abayomi, Khramtsova, Galina, Hurley, Ian, Popoola, Abiodun, Falusi, Adeyinka, Ogundiran, Temidayo, Obafunwa, John, Ojengbede, Oladosu, Ibrahim, Nasiru, Barretina, Jordi, White, Kevin P., Huo, Dezheng, Olopade, Olufunmilayo I.
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2019
Sujets:
Cancer Genetics and Epigenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851589/
https://ncbi.nlm.nih.gov/pubmed/31173346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32498
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