Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria

Somatic mutation signatures may represent footprints of genetic and environmental exposures that cause different cancer. Few studies have comprehensively examined their association with germline variants, and none in an indigenous African population. SomaticSignatures was employed to extract mutatio...

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Gepubliceerd in:Int J Cancer
Hoofdauteurs: Wang, Shengfeng, Pitt, Jason J., Zheng, Yonglan, Yoshimatsu, Toshio F., Gao, Guimin, Sanni, Ayodele, Oluwasola, Olayiwola, Ajani, Mustapha, Fitzgerald, Dominic, Odetunde, Abayomi, Khramtsova, Galina, Hurley, Ian, Popoola, Abiodun, Falusi, Adeyinka, Ogundiran, Temidayo, Obafunwa, John, Ojengbede, Oladosu, Ibrahim, Nasiru, Barretina, Jordi, White, Kevin P., Huo, Dezheng, Olopade, Olufunmilayo I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley & Sons, Inc. 2019
Onderwerpen:
Cancer Genetics and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851589/
https://ncbi.nlm.nih.gov/pubmed/31173346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.32498
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