Granulovacuolar degeneration bodies are neuron-selective lysosomal structures induced by intracellular tau pathology

Granulovacuolar degeneration bodies (GVBs) are membrane-bound vacuolar structures harboring a dense core that accumulate in the brains of patients with neurodegenerative disorders, including Alzheimer’s disease and other tauopathies. Insight into the origin of GVBs and their connection to tau pathol...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Wiersma, Vera I., van Ziel, Anna Maria, Vazquez-Sanchez, Sonia, Nölle, Anna, Berenjeno-Correa, Ernesto, Bonaterra-Pastra, Anna, Clavaguera, Florence, Tolnay, Markus, Musters, René J. P., van Weering, Jan R. T., Verhage, Matthijs, Hoozemans, Jeroen J. M., Scheper, Wiep
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851499/
https://ncbi.nlm.nih.gov/pubmed/31456031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02046-4
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