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Unconventional secretion factor GRASP55 is increased by pharmacological unfolded protein response inducers in neurons
Accumulation of misfolded proteins in the endoplasmic reticulum (ER), defined as ER stress, results in activation of the unfolded protein response (UPR). UPR activation is commonly observed in neurodegenerative diseases. ER stress can trigger unconventional secretion mediated by Golgi reassembly and...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6367349/ https://ncbi.nlm.nih.gov/pubmed/30733486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38146-6 |
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