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Ectopic Methylation of a Single Persistently Unmethylated CpG in the Promoter of the Vitellogenin Gene Abolishes Its Inducibility by Estrogen through Attenuation of Upstream Stimulating Factor Binding

The enhancer/promoter of the vitellogenin II gene (VTG) has been extensively studied as a model system of vertebrate transcriptional control. While deletion mutagenesis and in vivo footprinting identified the transcription factor (TF) binding sites governing its tissue specificity, DNase hypersensit...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Kallenberger, Lia, Erb, Rachel, Kralickova, Lucie, Patrignani, Andrea, Stöckli, Esther, Jiricny, Josef
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851352/
https://ncbi.nlm.nih.gov/pubmed/31548262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00436-19
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