Epidermal growth factor (EGF) triggers nuclear calcium signaling through the intranuclear phospholipase Cδ-4 (PLCδ4)

Calcium (Ca(2+)) signaling within the cell nucleus regulates specific cellular events such as gene transcription and cell proliferation. Nuclear and cytosolic Ca(2+) levels can be independently regulated, and nuclear translocation of receptor tyrosine kinases (RTKs) is one way to locally activate si...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: de Miranda, Marcelo Coutinho, Rodrigues, Michele Angela, de Angelis Campos, Ana Carolina, Faria, Jerusa Araújo Quintão Arantes, Kunrath-Lima, Marianna, Mignery, Gregory A., Schechtman, Deborah, Goes, Alfredo Miranda, Nathanson, Michael H., Gomes, Dawidson A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851314/
https://ncbi.nlm.nih.gov/pubmed/31537645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006961
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