Toll-like receptor 2–dependent endosomal signaling by Staphylococcus aureus in monocytes induces type I interferon and promotes intracellular survival

Pathogen activation of innate immune pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) stimulates cellular signaling pathways. This often leads to outcomes that contribute to pathogen clearance. Alternatively, activation of specific PRR pathways can aid pathogen survival. The h...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Musilova, Jana, Mulcahy, Michelle E., Kuijk, Marieke M., McLoughlin, Rachel M., Bowie, Andrew G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851302/
https://ncbi.nlm.nih.gov/pubmed/31558608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009302
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