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Transcriptomic Signatures Predict Regulators of Drug Synergy and Clinical Regimen Efficacy against Tuberculosis

The rapid spread of multidrug-resistant strains has created a pressing need for new drug regimens to treat tuberculosis (TB), which kills 1.8 million people each year. Identifying new regimens has been challenging due to the slow growth of the pathogen Mycobacterium tuberculosis (MTB), coupled with...

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Bibliographische Detailangaben
Veröffentlicht in:mBio
Hauptverfasser: Ma, Shuyi, Jaipalli, Suraj, Larkins-Ford, Jonah, Lohmiller, Jenny, Aldridge, Bree B., Sherman, David R., Chandrasekaran, Sriram
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851285/
https://ncbi.nlm.nih.gov/pubmed/31719182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02627-19
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