Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis

Although mouse infection models have been extensively used to study the host response to Mycobacterium tuberculosis, their validity in revealing determinants of human TB resistance and disease progression has been heavily debated. Here, we show that the modular transcriptional signature in the blood...

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Publicado en:Nat Immunol
Main Authors: Moreira-Teixeira, Lúcia, Tabone, Olivier, Graham, Christine M., Singhania, Akul, Stavropoulos, Evangelos, Redford, Paul S., Chakravarty, Probir, Priestnall, Simon L., Suarez-Bonnet, Alejandro, Herbert, Eleanor, Mayer-Barber, Katrin D., Sher, Alan, Fonseca, Kaori L., Sousa, Jeremy, Cá, Baltazar, Verma, Raman, Haldar, Pranabashis, Saraiva, Margarida, O’Garra, Anne
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116040/
https://ncbi.nlm.nih.gov/pubmed/32205882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0610-z
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