WMJ-S-001, a Novel Aliphatic Hydroxamate-Based Compound, Suppresses Lymphangiogenesis Through p38mapk-p53-survivin Signaling Cascade

Background and purpose: Angiogenesis and lymphangiogenesis are major routes for metastatic spread of tumor cells. It thus represent the rational targets for therapeutic intervention of cancer. Recently, we showed that a novel aliphatic hydroxamate-based compound, WMJ-S-001, exhibits anti-angiogenic,...

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Publicat a:Front Oncol
Autors principals: Huang, Shiu-Wen, Yang, Hung-Yu, Huang, Wei-Jan, Chen, Wei-Chuan, Yu, Meng-Chieh, Wang, Shih-Wei, Hsu, Ya-Fen, Hsu, Ming-Jen
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851263/
https://ncbi.nlm.nih.gov/pubmed/31781495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01188
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