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Alterations in ZnT1 expression and function lead to impaired intracellular zinc homeostasis in cancer

Zinc is vital for the structure and function of ~3000 human proteins and hence plays key physiological roles. Consequently, impaired zinc homeostasis is associated with various human diseases including cancer. Intracellular zinc levels are tightly regulated by two families of zinc transporters: ZIPs...

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Bibliografiske detaljer
Udgivet i:Cell Death Discov
Main Authors: Lehvy, Adrian Israel, Horev, Guy, Golan, Yarden, Glaser, Fabian, Shammai, Yael, Assaraf, Yehuda Gérard
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851190/
https://ncbi.nlm.nih.gov/pubmed/31728210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0224-0
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