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Alterations in ZnT1 expression and function lead to impaired intracellular zinc homeostasis in cancer

Zinc is vital for the structure and function of ~3000 human proteins and hence plays key physiological roles. Consequently, impaired zinc homeostasis is associated with various human diseases including cancer. Intracellular zinc levels are tightly regulated by two families of zinc transporters: ZIPs...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Discov
Hoofdauteurs: Lehvy, Adrian Israel, Horev, Guy, Golan, Yarden, Glaser, Fabian, Shammai, Yael, Assaraf, Yehuda Gérard
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851190/
https://ncbi.nlm.nih.gov/pubmed/31728210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0224-0
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