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Decreased APE-1 by Nitroxoline Enhances Therapeutic Effect in a Temozolomide-resistant Glioblastoma: Correlation with Diffusion Weighted Imaging

Glioblastoma multiforme (GBM) is one of the most aggressive human tumors with poor survival rates. The current standard treatment includes chemotherapy with temozolomide (TMZ), but acquisition of resistance is a persistent clinical problem limiting the successful treatment of GBM. The purpose of our...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Cho, Hye Rim, Kumari, Nisha, Thakur, Nishant, Vu, Hien Thi, Kim, Hyeonjin, Choi, Seung Hong
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851184/
https://ncbi.nlm.nih.gov/pubmed/31719653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53147-9
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