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Increased Antiangiogenic Effect by Blocking CCL2-dependent Macrophages in a Rodent Glioblastoma Model: Correlation Study with Dynamic Susceptibility Contrast Perfusion MRI

When glioblastoma multiforme (GBM) is treated with anti-vascular endothelial growth factor (VEGF) agents, it commonly exhibits tumor progression due to the development of resistance, which results in a dismal survival rate. GBM tumors contain a large number of monocytes/macrophages, which have been...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cho, Hye Rim, Kumari, Nisha, Thi Vu, Hien, Kim, Hyeonjin, Park, Chul-Kee, Choi, Seung Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668454/
https://ncbi.nlm.nih.gov/pubmed/31366997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47438-4
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