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Computational design and characterization of nanobody-derived peptides that stabilize the active conformation of the β(2)-adrenergic receptor (β(2)-AR)
This study aimed to design and functionally characterize peptide mimetics of the nanobody (Nb) related to the β(2)-adrenergic receptor (β(2)-AR) (nanobody-derived peptide, NDP). We postulated that the computationally derived and optimized complementarity-determining region 3 (CDR3) of Nb is sufficie...
में बचाया:
| में प्रकाशित: | Sci Rep |
|---|---|
| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Nature Publishing Group UK
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6851183/ https://ncbi.nlm.nih.gov/pubmed/31719570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52934-8 |
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