Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model

Cauda equina compression (CEC) is a major cause of neurogenic claudication and progresses to neuropathic pain (NP). A lipid mediator, lysophosphatidic acid (LPA), is known to induce NP via the LPA(1) receptor. To know a possible mechanism of LPA production in neurogenic claudication, we determined t...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Uranbileg, Baasanjav, Ito, Nobuko, Kurano, Makoto, Saigusa, Daisuke, Saito, Ritsumi, Uruno, Akira, Kano, Kuniyuki, Ikeda, Hitoshi, Yamada, Yoshitsugu, Sumitani, Masahiko, Sekiguchi, Miho, Aoki, Junken, Yatomi, Yutaka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6851136/
https://ncbi.nlm.nih.gov/pubmed/31719574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52999-5
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