miR‐200c suppresses stemness and increases cellular sensitivity to trastuzumab in HER2+ breast cancer

Resistance to trastuzumab remains a major obstacle in HER2‐overexpressing breast cancer treatment. miR‐200c is important for many functions in cancer stem cells (CSCs), including tumour recurrence, metastasis and resistance. We hypothesized that miR‐200c contributes to trastuzumab resistance and ste...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Tang, Hailin, Song, Cailu, Ye, Feng, Gao, Guanfeng, Ou, Xueqi, Zhang, Lijuan, Xie, Xinhua, Xie, Xiaoming
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850933/
https://ncbi.nlm.nih.gov/pubmed/31599500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14681
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