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Identification and Massively Parallel Characterization of Regulatory Elements Driving Neural Induction

Epigenomic regulation and lineage-specific gene expression act in concert to drive cellular differentiation, but the temporal interplay between these processes is largely unknown. Using neural induction from human pluripotent stem cells (hPSCs) as a paradigm, we interrogated these dynamics by perfor...

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Publié dans:Cell Stem Cell
Auteurs principaux: Inoue, Fumitaka, Kreimer, Anat, Ashuach, Tal, Ahituv, Nadav, Yosef, Nir
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850896/
https://ncbi.nlm.nih.gov/pubmed/31631012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.09.010
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