Once‐weekly prophylaxis with glycoPEGylated recombinant factor VIII (N8‐GP) in severe haemophilia A: Safety and efficacy results from pathfinder 2 (randomized phase III trial)

INTRODUCTION: Turoctocog alfa pegol (N8‐GP) is a site‐specific, 40 kDa glycoPEGylated recombinant factor VIII (FVIII) product with an extended half‐life. The comprehensive main phase of the pivotal pathfinder 2 trial showed N8‐GP dosed every 4 days (Q4D) provided favourable safety and efficacy for p...

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Detalhes bibliográficos
Publicado no:Haemophilia
Main Authors: Curry, Nicola, Albayrak, Canan, Escobar, Miguel, Andre Holme, Pål, Kearney, Susan, Klamroth, Robert, Misgav, Mudi, Négrier, Claude, Wheeler, Allison, Santagostino, Elena, Shima, Midori, Landorph, Andrea, Tønder, Sidsel Marie, Lentz, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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ORIGINAL ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850405/
https://ncbi.nlm.nih.gov/pubmed/30817066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/hae.13712
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