Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression

Understanding the mechanisms that promote the specification of pancreas progenitors and regulate their self‐renewal and differentiation will help to maintain and expand pancreas progenitor cells derived from human pluripotent stem (hPS) cells. This will improve the efficiency of current differentiat...

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Vydáno v:Stem Cells
Hlavní autoři: Giannios, Ioannis, Serafimidis, Ioannis, Anastasiou, Vivian, Pezzolla, Daniela, Lesche, Mathias, Andree, Cordula, Bickle, Marc, Gavalas, Anthony
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2019
Témata:
Regenerative Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850398/
https://ncbi.nlm.nih.gov/pubmed/30681750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2979
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