Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression

Understanding the mechanisms that promote the specification of pancreas progenitors and regulate their self‐renewal and differentiation will help to maintain and expand pancreas progenitor cells derived from human pluripotent stem (hPS) cells. This will improve the efficiency of current differentiat...

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Bibliografiske detaljer
Udgivet i:Stem Cells
Main Authors: Giannios, Ioannis, Serafimidis, Ioannis, Anastasiou, Vivian, Pezzolla, Daniela, Lesche, Mathias, Andree, Cordula, Bickle, Marc, Gavalas, Anthony
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2019
Fag:
Regenerative Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850398/
https://ncbi.nlm.nih.gov/pubmed/30681750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2979
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