Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression

Understanding the mechanisms that promote the specification of pancreas progenitors and regulate their self‐renewal and differentiation will help to maintain and expand pancreas progenitor cells derived from human pluripotent stem (hPS) cells. This will improve the efficiency of current differentiat...

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Опубликовано в: :Stem Cells
Главные авторы: Giannios, Ioannis, Serafimidis, Ioannis, Anastasiou, Vivian, Pezzolla, Daniela, Lesche, Mathias, Andree, Cordula, Bickle, Marc, Gavalas, Anthony
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Inc. 2019
Предметы:
Regenerative Medicine
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6850398/
https://ncbi.nlm.nih.gov/pubmed/30681750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2979
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