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Safety of allogeneic hematopoietic cell transplant in adults after CD19-targeted CAR T-cell therapy

Allogeneic hematopoietic cell transplantation (allo-HCT) is offered to selected patients after chimeric antigen receptor–modified T-cell (CAR-T) therapy. Lymphodepleting chemotherapy and CAR-T therapy have immunosuppressive and immunomodulatory effects that could alter the safety profile of subseque...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Shadman, Mazyar, Gauthier, Jordan, Hay, Kevin A., Voutsinas, Jenna M., Milano, Filippo, Li, Ang, Hirayama, Alexandre V., Sorror, Mohamed L., Cherian, Sindhu, Chen, Xueyan, Cassaday, Ryan D., Till, Brian G., Gopal, Ajay K., Sandmaier, Brenda M., Maloney, David G., Turtle, Cameron J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849954/
https://ncbi.nlm.nih.gov/pubmed/31648329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000593
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