Ring sideroblasts in AML are associated with adverse risk characteristics and have a distinct gene expression pattern

Ring sideroblasts (RS) emerge as result of aberrant erythroid differentiation leading to excessive mitochondrial iron accumulation, a characteristic feature for myelodysplastic syndromes (MDS) with mutations in the spliceosome gene SF3B1. However, RS can also be observed in patients diagnosed with a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Berger, Gerbrig, Gerritsen, Mylene, Yi, Guoqiang, Koorenhof-Scheele, Theresia N., Kroeze, Leonie I., Stevens-Kroef, Marian, Yoshida, Kenichi, Shiraishi, Yuichi, van den Berg, Eva, Schepers, Hein, Huls, Geert, Mulder, André B., Ogawa, Seishi, Martens, Joost H. A., Jansen, Joop H., Vellenga, Edo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Myeloid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849935/
https://ncbi.nlm.nih.gov/pubmed/31648334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000518
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados