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Therapeutic Effects of Nrf2 Activation by Bardoxolone Methyl in Chronic Heart Failure
Oxidative stress plays an important role in the pathogenesis of chronic heart failure (CHF) in many tissues. Increasing evidence suggests that systemic activation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) signaling can protect against postinfarct cardiac remodeling by reducing oxidative...
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| Publicado en: | J Pharmacol Exp Ther |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6849407/ https://ncbi.nlm.nih.gov/pubmed/31601682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.261792 |
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