Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency

BACKGROUND: HIV-infected cell lines are widely used to study latent HIV infection, which is considered the main barrier to HIV cure. We hypothesized that these cell lines differ from each other and from cells from HIV-infected individuals in the mechanisms underlying latency. RESULTS: To quantify th...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Telwatte, Sushama, Morón-López, Sara, Aran, Dvir, Kim, Peggy, Hsieh, Christine, Joshi, Sunil, Montano, Mauricio, Greene, Warner C., Butte, Atul J., Wong, Joseph K., Yukl, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849327/
https://ncbi.nlm.nih.gov/pubmed/31711503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-019-0494-x
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