Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency

BACKGROUND: HIV-infected cell lines are widely used to study latent HIV infection, which is considered the main barrier to HIV cure. We hypothesized that these cell lines differ from each other and from cells from HIV-infected individuals in the mechanisms underlying latency. RESULTS: To quantify th...

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Enregistré dans:
Détails bibliographiques
Publié dans:Retrovirology
Auteurs principaux: Telwatte, Sushama, Morón-López, Sara, Aran, Dvir, Kim, Peggy, Hsieh, Christine, Joshi, Sunil, Montano, Mauricio, Greene, Warner C., Butte, Atul J., Wong, Joseph K., Yukl, Steven A.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849327/
https://ncbi.nlm.nih.gov/pubmed/31711503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-019-0494-x
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