Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency

BACKGROUND: HIV-infected cell lines are widely used to study latent HIV infection, which is considered the main barrier to HIV cure. We hypothesized that these cell lines differ from each other and from cells from HIV-infected individuals in the mechanisms underlying latency. RESULTS: To quantify th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Retrovirology
Main Authors: Telwatte, Sushama, Morón-López, Sara, Aran, Dvir, Kim, Peggy, Hsieh, Christine, Joshi, Sunil, Montano, Mauricio, Greene, Warner C., Butte, Atul J., Wong, Joseph K., Yukl, Steven A.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849327/
https://ncbi.nlm.nih.gov/pubmed/31711503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-019-0494-x
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