Evolution and Impact of Subclonal Mutations in Papillary Thyroid Cancer

Unlike many cancers, the pattern of tumor evolution in papillary thyroid cancer (PTC) and its potential role in relapse have not been elucidated. In this study, multi-region whole-exome sequencing (WES) was performed on early-stage PTC tumors (n = 257 tumor regions) from 79 individuals, including 17...

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Vydáno v:Am J Hum Genet
Hlavní autoři: Masoodi, Tariq, Siraj, Abdul K., Siraj, Sarah, Azam, Saud, Qadri, Zeeshan, Parvathareddy, Sandeep K., Al-Sobhi, Saif S., AlDawish, Mohammed, Alkuraya, Fowzan S., Al-Kuraya, Khawla S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6849094/
https://ncbi.nlm.nih.gov/pubmed/31668701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.09.026
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