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Prognostic Significance of COX-2 Overexpression in BRAF-Mutated Middle Eastern Papillary Thyroid Carcinoma

The cyclooxygenase-2 (COX-2)–prostaglandin E2 (PGE2) pathway has been implicated in carcinogenesis, with BRAF mutation shown to promote PGE2 synthesis. This study was conducted to evaluate COX-2 expression in a large cohort of Middle Eastern papillary thyroid carcinoma (PTC), and further evaluate th...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Parvathareddy, Sandeep Kumar, Siraj, Abdul K., Annaiyappanaidu, Padmanaban, Al-Sobhi, Saif S., Al-Dayel, Fouad, Al-Kuraya, Khawla S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7764962/
https://ncbi.nlm.nih.gov/pubmed/33327467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21249498
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