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Estimating the Genome-wide Mutation Rate with Three-Way Identity by Descent

The two primary methods for estimating the genome-wide mutation rate have been counting de novo mutations in parent-offspring trios and comparing sequence data between closely related species. With parent-offspring trio analysis it is difficult to control for genotype error, and resolution is limite...

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Detalles Bibliográficos
Publicado en:Am J Hum Genet
Main Authors: Tian, Xiaowen, Browning, Brian L., Browning, Sharon R.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848988/
https://ncbi.nlm.nih.gov/pubmed/31587867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2019.09.012
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