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Detecting Identity by Descent and Estimating Genotype Error Rates in Sequence Data
Existing methods for identity by descent (IBD) segment detection were designed for SNP array data, not sequence data. Sequence data have a much higher density of genetic variants and a different allele frequency distribution, and can have higher genotype error rates. Consequently, best practices for...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824133/ https://ncbi.nlm.nih.gov/pubmed/24207118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.09.014 |
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