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Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge

Aging is associated with an exaggerated response to peripheral inflammatory challenges together with behavioral and cognitive deficits. Studies considering both age and sex remain limited, despite sex dimorphism of astrocytes and microglial cells is largely recognized. To fill this knowledge gap, we...

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Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: Murtaj, Valentina, Belloli, Sara, Di Grigoli, Giuseppe, Pannese, Maria, Ballarini, Elisa, Rodriguez-Menendez, Virginia, Marmiroli, Paola, Cappelli, Andrea, Masiello, Valeria, Monterisi, Cristina, Bellelli, Giuseppe, Panina-Bordignon, Paola, Moresco, Rosa Maria
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848890/
https://ncbi.nlm.nih.gov/pubmed/31749696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00299
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