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Personalised Warfarin Dosing in Children Post-cardiac Surgery
Warfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics (PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a warfarin PK/PD model and incorporating CYP2C9 and VKORC1 genotype information has been developed for children. The present...
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| Publicado no: | Pediatr Cardiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6848240/ https://ncbi.nlm.nih.gov/pubmed/31587090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00246-019-02215-y |
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