Personalised Warfarin Dosing in Children Post-cardiac Surgery

Warfarin dosing is challenging due to a multitude of factors affecting its pharmacokinetics (PK) and pharmacodynamics (PD). A novel personalised dosing algorithm predicated on a warfarin PK/PD model and incorporating CYP2C9 and VKORC1 genotype information has been developed for children. The present...

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Bibliografiske detaljer
Udgivet i:Pediatr Cardiol
Main Authors: Al-Metwali, Basma Zuheir, Rivers, Peter, Goodyer, Larry, O’Hare, Linda, Young, Sanfui, Mulla, Hussain
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2019
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848240/
https://ncbi.nlm.nih.gov/pubmed/31587090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00246-019-02215-y
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