Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish

Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and the depletion of the glutathione (GSx) stores in neural tissue. The use of N-acetylcysteine (NAC)...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Faria, Melissa, Prats, Eva, Gómez-Canela, Cristian, Hsu, Chuan-Yu, Arick, Mark A., Bedrossiantz, Juliette, Orozco, Manuel, Garcia-Reyero, Natàlia, Ziv, Tamar, Ben-Lulu, Shani, Admon, Arie, Gómez-Oliván, Leobardo Manuel, Raldúa, Demetrio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848153/
https://ncbi.nlm.nih.gov/pubmed/31712630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53154-w
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