Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish

Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and the depletion of the glutathione (GSx) stores in neural tissue. The use of N-acetylcysteine (NAC)...

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Publicado no:Sci Rep
Main Authors: Faria, Melissa, Prats, Eva, Gómez-Canela, Cristian, Hsu, Chuan-Yu, Arick, Mark A., Bedrossiantz, Juliette, Orozco, Manuel, Garcia-Reyero, Natàlia, Ziv, Tamar, Ben-Lulu, Shani, Admon, Arie, Gómez-Oliván, Leobardo Manuel, Raldúa, Demetrio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848153/
https://ncbi.nlm.nih.gov/pubmed/31712630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53154-w
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