Therapeutic potential of N-acetylcysteine in acrylamide acute neurotoxicity in adult zebrafish

Two essential key events in acrylamide (ACR) acute neurotoxicity are the formation of adducts with nucleophilic sulfhydryl groups on cysteine residues of selected proteins in the synaptic terminals and the depletion of the glutathione (GSx) stores in neural tissue. The use of N-acetylcysteine (NAC)...

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Publicat a:Sci Rep
Autors principals: Faria, Melissa, Prats, Eva, Gómez-Canela, Cristian, Hsu, Chuan-Yu, Arick, Mark A., Bedrossiantz, Juliette, Orozco, Manuel, Garcia-Reyero, Natàlia, Ziv, Tamar, Ben-Lulu, Shani, Admon, Arie, Gómez-Oliván, Leobardo Manuel, Raldúa, Demetrio
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6848153/
https://ncbi.nlm.nih.gov/pubmed/31712630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53154-w
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