EXTH-32. DEVELOPMENT OF EPHA3 DIRECTED CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME

BACKGROUND: Efficacy of chimeric antigen receptor T cell (CART) therapy remains limited in solid tumors. Given the heterogeneity of surface receptor expression and immunosuppressive stromal microenvironment, strategies to target tumor neovasculature and tumor stromal cells are needed to help overcom...

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Publicat a:Neuro Oncol
Autors principals: Ruff, Michael, Sakemura, Reona, Cox, Michelle, Hefazi Torghabeh, Mehrdad, Roman Moreno, Paulina, Schick, Kendall, Sarkaria, Jann, Kenderian, Saad
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847906/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.364
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