EXTH-32. DEVELOPMENT OF EPHA3 DIRECTED CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY FOR THE TREATMENT OF GLIOBLASTOMA MULTIFORME

BACKGROUND: Efficacy of chimeric antigen receptor T cell (CART) therapy remains limited in solid tumors. Given the heterogeneity of surface receptor expression and immunosuppressive stromal microenvironment, strategies to target tumor neovasculature and tumor stromal cells are needed to help overcom...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Ruff, Michael, Sakemura, Reona, Cox, Michelle, Hefazi Torghabeh, Mehrdad, Roman Moreno, Paulina, Schick, Kendall, Sarkaria, Jann, Kenderian, Saad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847906/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.364
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