RDNA-12. THE FANCONI ANAEMIA (FA) PATHWAY AND GLIOBLASTOMA: A NEW FOUNDATION FOR DNA DAMAGE RESPONSE TARGETED COMBINATIONS

Treatment resistance in glioblastoma is underpinned by highly interconnected DNA damage response (DDR) processes. The FA-pathway is a fundamental DDR process required for the resolution of replication fork impeding lesions, and we have previously shown that it is inactive in normal brain, but is re-...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Neuro Oncol
Главные авторы: Rominiyi, Ola, Myers, Katie, Gomez-Roman, Natividad, Lad, Nikita, Dar, Dawoud, Jellinek, David, Chalmers, Anthony, Carroll, Thomas, Chen, Beining, Al-Tamimi, Yahia, Collis, Spencer
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2019
Предметы:
Radiation Biology and DNA Repair
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847875/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.871
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы