RDNA-11. LOW MITOCHONDRIAL DNA CONTENT INDUCES TREATMENT RESISTANCE AND CONFERS POOR PROGNOSIS IN GLIOBLASTOMA

BACKGROUND: Investigation of mitochondrial DNA (mtDNA) content in glioblastoma has gathered speed in recent years. Our study focusses on the effect of mtDNA content depletion on treatment response in glioblastoma. MATERIALS AND METHODS: The study consists of a survival cohort (n=130), a recurrent co...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Sravya, Palavalasa, Nimbalkar, Vidya, Kanuri, Nandaki, Sugur, Harsha, Rao, Shilpa, Somanna, Sampath, Kondaiah, Paturu, Arimappamagan, Arivazhagan, Santosh, Vani
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Radiation Biology and DNA Repair
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847797/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.870
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