RDNA-11. LOW MITOCHONDRIAL DNA CONTENT INDUCES TREATMENT RESISTANCE AND CONFERS POOR PROGNOSIS IN GLIOBLASTOMA

BACKGROUND: Investigation of mitochondrial DNA (mtDNA) content in glioblastoma has gathered speed in recent years. Our study focusses on the effect of mtDNA content depletion on treatment response in glioblastoma. MATERIALS AND METHODS: The study consists of a survival cohort (n=130), a recurrent co...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Sravya, Palavalasa, Nimbalkar, Vidya, Kanuri, Nandaki, Sugur, Harsha, Rao, Shilpa, Somanna, Sampath, Kondaiah, Paturu, Arimappamagan, Arivazhagan, Santosh, Vani
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Radiation Biology and DNA Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847797/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.870
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