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RDNA-11. LOW MITOCHONDRIAL DNA CONTENT INDUCES TREATMENT RESISTANCE AND CONFERS POOR PROGNOSIS IN GLIOBLASTOMA

BACKGROUND: Investigation of mitochondrial DNA (mtDNA) content in glioblastoma has gathered speed in recent years. Our study focusses on the effect of mtDNA content depletion on treatment response in glioblastoma. MATERIALS AND METHODS: The study consists of a survival cohort (n=130), a recurrent co...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Sravya, Palavalasa, Nimbalkar, Vidya, Kanuri, Nandaki, Sugur, Harsha, Rao, Shilpa, Somanna, Sampath, Kondaiah, Paturu, Arimappamagan, Arivazhagan, Santosh, Vani
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847797/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.870
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