RBTT-05. A SINGLE-ARM, OPEN-LABEL, PHASE II STUDY EVALUATING THE EFFICACY AND SAFETY OF ABEMACICLIB IN PATIENTS WITH RECURRENT OLIGODENDROGLIOMA: TRIALS IN PROGRESS

BACKGROUND: Oligodendroglioma is a rare primary brain tumor characterized by mutation in the IDH1/IDH2 genes and codeletion of chromosomes 1p and 19q. Although median overall survival extends beyond 10 years for patients with oligodendroglioma who receive adjuvant radiation and alkylating chemothera...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Bagley, Stephen, Nasrallah, MacLean, O’Rourke, Donald, Hussain, Jasmin, Maloney-Wilensky, Eileen, Prior, Timothy, Brem, Steven, Desai, Arati
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
Randomized Brain Tumor Trials in Development
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847756/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.917
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