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NIMG-60. IDH MUTANT GLIOMAS WITH 1p/19q CO-DELETION ARE LESS ACIDIC THAN NON-CO-DELETED GLIOMAS AS MEASURED WITH PH-WEIGHTED AMINE CEST-MRI AND AMINO ACID PET

1p/19q co-deleted gliomas are known to have slower growth rates and are more sensitive to chemotherapy and radiotherapy. This may be partially explained by the lower tumor acidosis compared to non-co-deleted gliomas, as extracellular acidosis is one of the driving forces toward tumor invasion and re...

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Bibliografiske detaljer
Udgivet i:Neuro Oncol
Main Authors: Yao, Jingwen, Nathanson, David, Yong, William H, Salamon, Noriko, Lai, Albert, Leia Nghiemphu, P, Prins, Robert, Pope, Whitney, Czernin, Johannes, Everson, Richard, Liau, Linda, Cloughesy, Timothy, Ellingson, Benjamin
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847744/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.729
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