EXTH-47. THERAPEUTIC REVERSAL OF PRENATAL PONTINE ID1 SIGNALING IN DIPG

Diffuse intrinsic pontine gliomas (DIPGs) are lethal brain tumors with no effective therapies other than radiation. Inhibitor of DNA binding (ID) proteins are key regulators of tissue and lineage-specific gene differentiation during embryogenesis. Previous work has shown that H3F3A and ACVR1 mutatio...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Harris, Micah, Yadav, Vivekanand, Stallard, Stefanie, Woo, Rinette, Siddaway, Robert, Qin, Tingting, Mullan, Brendan, Miklja, Zachary, Siada, Ruby, Ravindran, Ramya, Cao, Xuhong, Pasternak, Amy, Castro, Maria, Lowenstein, Pedro, Mody, Rajen, Chinnaiyan, Arul, Hawkins, Cynthia, McAllister, Sean, Desprez, Pierre, Venneti, Sriram, Koschmann, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847584/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.379
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