ANGI-03. PHARMACOLOGICAL TARGETING OF APELIN/APLNR SIGNALING BLUNTS THERAPY RESISTANCE TO VEGFA/VEGFR2 ANTI-ANGIOGENIC TREATMENT IN GLIOBLASTOMA

Anti-angiogenic therapy of glioblastoma with bevacizumab, a vascular endothelial growth factor-A (VEGFA) blocking antibody, may accelerate tumor cell invasion and induce alternative angiogenic pathways. We investigated the roles of the pro-angiogenic receptor APLNR and its cognate ligand apelin in V...

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Vydáno v:Neuro Oncol
Hlavní autoři: Kälin, Roland, Mastrella, Giorgia, Hou, Mengzhuo, Li, Min, Stoecklein, Veit, Zdouc, Nina, Volmar, Marie, Miletic, Hrvoje, Reinhard, Sören, Herold-Mende, Christel, Kleber, Susanne, Eisenhut, Katharina, Gargiulo, Gaetano, Synowitz, Michael, Vescovi, Angelo, Harter, Patrick, Penninger, Josef, Wagner, Ernst, Mittelbronn, Michel, Bjerkvig, Rolf, Hambardzumyan, Dolores, Schüller, Ulrich, Tonn, Joerg-Christian, Radke, Josefine, Glass, Rainer
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Angiogenesis and Invasion
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847580/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.114
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