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STEM-25. HDAC1 IS ESSENTIAL FOR GLIOMA STEM CELL SURVIVAL

OLIG2 is a central nervous system-specific transcription factor that is expressed in almost all diffuse gliomas. It is also one of the key core transcription factors that can reprogram differentiated glioma cells to highly tumorigenic glioma stem-like cells (GSCs). We have previously shown that expr...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Lo Cascio, Costanza, McNamara, James, Luna Melendez, Ernesto, Mehta, Shwetal
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847567/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.998
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