STEM-25. DIFFERENTIAL REGULATION OF GLIOMA STEM-CELL MARKER NESTIN AND CD24 IN IDH-MUTANT GLIOMA

Heterozygous mutations in the isocitrate dehydrogenase 1 (IDH1) gene are most common in glioma, resulting in predominantly arginine to histidine substitution at codon 132. Because IDH1(R132H) requires a wild-type allele to produce (D)-2-hydroxyglutarate for epigenetic reprogramming, glioma cells wit...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Tiburcio, Patricia, Locke, Mary, Bhaskara, Srivydia, Chandrasekharan, Mahesh, Huang, Eric
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Cancer Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7651546/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa215.842
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