Phosphorylation of Drosophila CENP-A on serine 20 regulates protein turn-over and centromere-specific loading

Centromeres are specialized chromosomal regions epigenetically defined by the presence of the histone H3 variant CENP-A. CENP-A is required for kinetochore formation which is essential for chromosome segregation during mitosis. Spatial restriction of CENP-A to the centromere is tightly controlled. I...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Huang, Anming, Kremser, Leopold, Schuler, Fabian, Wilflingseder, Doris, Lindner, Herbert, Geley, Stephan, Lusser, Alexandra
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847487/
https://ncbi.nlm.nih.gov/pubmed/31535131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz809
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